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These alterations create a vicious cycle of mitochondrial dysfunction, oxidative injury, and myofiber apoptosis, ultimately leading to irreversible supraspinatus atrophy and impaired regeneration after rotator cuff tears
These medications mimic the effects of the naturally occurring GLP-1 hormone, which is produced in the intestines and helps regulate insulin secretion, appetite, and food intake
In contrast, clinical studies show that people taking semaglutide 2.4 mg once weekly (available as Wegovy, but similar to a 2 mg weekly dose of Ozempic) experienced an average weight loss of 15% over 68 weeks
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